A biosensing system using a multiparameter nonlinear dynamic analysis of cardiomyocyte beating for drug-induced arrhythmia recognition

Abstract Cardiovascular disease is the number one cause of death in humans. Therefore, cardiotoxicity is one of the most important adverse effects assessed by arrhythmia recognition in drug development. Recently, cell-based techniques developed for arrhythmia recognition primarily employ linear meth...

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Bibliographic Details
Main Authors: Hao Wang, Yue Wu, Quchao Zou, Wenjian Yang, Zhongyuan Xu, Hao Dong, Zhijing Zhu, Depeng Wang, Tianxing Wang, Ning Hu, Diming Zhang
Format: Article
Language:English
Published: Nature Publishing Group 2022-05-01
Series:Microsystems & Nanoengineering
Online Access:https://doi.org/10.1038/s41378-022-00383-1