A comparison of topologically associating domain callers over mammals at high resolution

A comparison of topologically associating domain callers over mammals at high resolution

Abstract Background Topologically associating domains (TADs) are locally highly-interacting genome regions, which also play a critical role in regulating gene expression in the cell. TADs have been first identified while investigating the 3D genome structure over High-throughput Chromosome Conformat...

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Bibliographic Details
Main Author: Emre Sefer
Format: Article
Language:English
Published: BMC 2022-04-01
Series:BMC Bioinformatics
Subjects:
Chromatin organization
Hi-C
Micro-C
Topologically associating domains
TAD callers
Online Access:https://doi.org/10.1186/s12859-022-04674-2

Internet

https://doi.org/10.1186/s12859-022-04674-2

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