LAG-3 Expression Predicts Outcome in Stage II Colon Cancer

LAG-3 Expression Predicts Outcome in Stage II Colon Cancer

Introduction: LAG-3 is an inhibitory immune checkpoint molecule that suppresses T cell activation and inflammatory cytokine secretion. T cell density in the tumor microenvironment of colon cancer plays an important role in the host’s immunosurveillance. We therefore hypothesized that LAG-3 expressio...

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Bibliographic Details
Main Authors: Gaëlle Rhyner Agocs, Naziheh Assarzadegan, Richard Kirsch, Heather Dawson, José A. Galván, Alessandro Lugli, Inti Zlobec, Martin D. Berger
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Journal of Personalized Medicine
Subjects:
biomarker
LAG-3
immune checkpoint
colon cancer
survival
Online Access:https://www.mdpi.com/2075-4426/11/8/749

Internet

https://www.mdpi.com/2075-4426/11/8/749

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