Toosendanin From Melia Fructus Suppresses Influenza A Virus Infection by Altering Nuclear Localization of Viral Polymerase PA Protein

Toosendanin From Melia Fructus Suppresses Influenza A Virus Infection by Altering Nuclear Localization of Viral Polymerase PA Protein

Toosendanin (TSN) is a major bioactive component of Melia Fructus (MF) with anti-inflammatory, anti-botulinum, anti-microbial, and analgesic efficacy. Our previous study demonstrated that MF has anti-influenza A virus activity; however, the contribution of TSN is still unclear. In this study, we fou...

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Bibliographic Details
Main Authors: Young-Hee Jin, Sunoh Kwon, Jang-Gi Choi, Won-Kyung Cho, Bonggi Lee, Jin Yeul Ma
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-09-01
Series:Frontiers in Pharmacology
Subjects:
toosendanin
Melia Fructus
influenza A virus
polymerase acidic protein
anti-viral activity
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.01025/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2019.01025/full

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