Patellar instability-induced bone loss in the femoral trochlea is associated with the activation of the JAK1/STAT3 signaling pathway in growing mice

Patellar instability-induced bone loss in the femoral trochlea is associated with the activation of the JAK1/STAT3 signaling pathway in growing mice

Abstract Introduction Patellar instability (PI) at an early age is believed closely correlated with bone loss in the development of the femoral trochlea and can cause trochlear dysplasia. However, the molecular mechanism of PI-induced bone loss has not been established. The Janus kinase (JAK)/signal...

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Bibliographic Details
Main Authors: Chen Ma, Wenguan Kou, Zhaoxia Cui, Wenfeng Liu, Changli Liu, Shengjie Wang, Fei Wang
Format: Article
Language:English
Published: BMC 2023-07-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
Patellar instability
Trochlear dysplasia
Bone loss
JAK1/STAT3
Mice
Online Access:https://doi.org/10.1186/s13018-023-04019-6

Internet

https://doi.org/10.1186/s13018-023-04019-6

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