A Novel 3D Model for Visualization and Tracking of Fibroblast-Guided Directional Cancer Cell Migration

Stromal fibroblasts surrounding cancer cells are a major and important constituent of the tumor microenvironment not least because they contain cancer-associated fibroblasts, a unique fibroblastic cell type that promotes tumorigenicity through extracellular matrix remodeling and secretion of soluble...

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Bibliographic Details
Main Authors: Yihe Zhang, Bingjie Jiang, Meng Huee Lee
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Biology
Subjects:
Online Access:https://www.mdpi.com/2079-7737/9/10/328