Sensing and integration of Erk and PI3K signals by Myc.

The transcription factor Myc plays a central role in regulating cell-fate decisions, including proliferation, growth, and apoptosis. To maintain a normal cell physiology, it is critical that the control of Myc dynamics is precisely orchestrated. Recent studies suggest that such control of Myc can be...

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Bibliographic Details
Main Authors: Tae Lee, Guang Yao, Joseph Nevins, Lingchong You
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-02-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC2265471?pdf=render