Profiling the Effects of Systemic Antibiotics for Acne, Including the Narrow-Spectrum Antibiotic Sarecycline, on the Human Gut Microbiota

Profiling the Effects of Systemic Antibiotics for Acne, Including the Narrow-Spectrum Antibiotic Sarecycline, on the Human Gut Microbiota

Treatment for moderate-to-severe acne vulgaris relies on prolonged use of oral tetracycline-class antibiotics; however, these broad-spectrum antibiotics are often associated with off-target effects and negative gastrointestinal sequelae. Sarecycline is a narrow-spectrum antibiotic treatment option....

Full description

Bibliographic Details
Main Authors: Ines B. Moura, Ayman Grada, William Spittal, Emma Clark, Duncan Ewin, James Altringham, Emilio Fumero, Mark H. Wilcox, Anthony M. Buckley
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Microbiology
Subjects:
sarecycline
acne (acne vulgaris)
long-term antibiotic treatment
gut microbiota
in vitro model
minocycline
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2022.901911/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2022.901911/full

Similar Items