Global mapping of H3K4me1 and H3K4me3 reveals the chromatin state-based cell type-specific gene regulation in human Treg cells.

Regulatory T cells (Treg) contribute to the crucial immunological processes of self-tolerance and immune homeostasis. Genomic mechanisms that regulate cell fate decisions leading to Treg or conventional T cells (Tconv) lineages and those underlying Treg function remain to be fully elucidated, especi...

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Bibliographic Details
Main Authors: Yi Tian, Zhengcai Jia, Jun Wang, Zemin Huang, Jun Tang, Yanhua Zheng, Yan Tang, Qinghong Wang, Zhiqiang Tian, Di Yang, Yi Zhang, Xiaolan Fu, Jianxun Song, Shunli Liu, Jennifer C van Velkinburgh, Yuzhang Wu, Bing Ni
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3223197?pdf=render