Mechanism and therapeutic potential of targeting cGAS-STING signaling in neurological disorders
Abstract DNA sensing is a pivotal component of the innate immune system that is responsible for detecting mislocalized DNA and triggering downstream inflammatory pathways. Among the DNA sensors, cyclic GMP-AMP synthase (cGAS) is a primary player in detecting cytosolic DNA, including foreign DNA from...
| Główni autorzy: | , , , , |
|---|---|
| Format: | Artykuł |
| Język: | English |
| Wydane: |
BMC
2023-11-01
|
| Seria: | Molecular Neurodegeneration |
| Hasła przedmiotowe: | |
| Dostęp online: | https://doi.org/10.1186/s13024-023-00672-x |