Bazi Bushen capsule improves the deterioration of the intestinal barrier function by inhibiting NLRP3 inflammasome-mediated pyroptosis through microbiota-gut-brain axis

Bazi Bushen capsule improves the deterioration of the intestinal barrier function by inhibiting NLRP3 inflammasome-mediated pyroptosis through microbiota-gut-brain axis

PurposeThe senescence-accelerated prone mouse 8 (SAMP8) is a widely used model for accelerating aging, especially in central aging. Mounting evidence indicates that the microbiota-gut-brain axis may be involved in the pathogenesis and progression of central aging-related diseases. This study aims to...

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Bibliographic Details
Main Authors: Shixiong Zhang, Mengnan Li, Liping Chang, Xinjing Mao, Yuning Jiang, Xiaogang Shen, Kunxu Niu, Xuan Lu, Runtao Zhang, Yahui Song, Kun Ma, Hongrong Li, Cong Wei, Yunlong Hou, Yiling Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Microbiology
Subjects:
intestinal barrier function
microbiota-gut-brain axis
inflammasome
pyroptosis
SAMP8
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2023.1320202/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2023.1320202/full

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