Panel Sequencing for Clinically Oriented Variant Screening and Copy Number Detection in Chronic Lymphocytic Leukemia Patients

Panel Sequencing for Clinically Oriented Variant Screening and Copy Number Detection in Chronic Lymphocytic Leukemia Patients

According to current guidelines, in chronic lymphocytic leukemia (CLL), only the <i>TP53</i> molecular status must be evaluated prior to every treatment’s initiation. However, additional heterogeneous genetic events are known to confer a proliferative advantage to the tumor clone and are...

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Bibliographic Details
Main Authors: Mariam Ibáñez, Esperanza Such, Alessandro Liquori, Gayane Avestisyan, Rafael Andreu, Ana Vicente, María José Macián, Mari Carmen Melendez, Mireya Morote-Faubel, Pedro Asensi, María Pilar Lloret, Isidro Jarque, Isabel Picón, Alejandro Pacios, Eva Donato, Carmen Mas-Ochoa, Carmen Alonso, Carolina Cañigral, Amparo Sempere, Samuel Romero, Marta Santiago, Guillermo F. Sanz, Javier de la Rubia, Leonor Senent, Irene Luna
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Diagnostics
Subjects:
CLL
NGS target panel
somatic variants and CNVs
prognostic and/or predictive genes
Online Access:https://www.mdpi.com/2075-4418/12/4/953

Internet

https://www.mdpi.com/2075-4418/12/4/953

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