Design, Synthesis and Biological Evaluation of New HDAC1 and HDAC2 Inhibitors Endowed with Ligustrazine as a Novel Cap Moiety

Design, Synthesis and Biological Evaluation of New HDAC1 and HDAC2 Inhibitors Endowed with Ligustrazine as a Novel Cap Moiety

Mohammad M Al-Sanea,1 Lizaveta Gotina,2 Mamdouh FA Mohamed,3 Della Grace Thomas Parambi,1 Hesham A M Gomaa,4,5 Bijo Mathew,6 Bahaa G M Youssif,7 Khalid Saad Alharbi,8 Zainab M Elsayed,9 Mohamed A Abdelgawad,1,10 Wagdy M Eldehna9,11 1Department of Pharmaceutical Chemistry, College of Pharmacy, Jouf U...

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Bibliographic Details
Main Authors: Al-Sanea MM, Gotina L, Mohamed MFA, Grace Thomas Parambi D, Gomaa HAM, Mathew B, Youssif BGM, Alharbi KS, Elsayed ZM, Abdelgawad MA, Eldehna WM
Format: Article
Language:English
Published: Dove Medical Press 2020-02-01
Series:Drug Design, Development and Therapy
Subjects:
hdacs inhibitors
ligustrazine
anticancer agents
in silico study
synthesis
Online Access:https://www.dovepress.com/design-synthesis-and-biological-evaluation-of-new-hdac1-and-hdac2-inhi-peer-reviewed-article-DDDT

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https://www.dovepress.com/design-synthesis-and-biological-evaluation-of-new-hdac1-and-hdac2-inhi-peer-reviewed-article-DDDT

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