Naphthalimide-Containing BP100 Leads to Higher Model Membranes Interactions and Antimicrobial Activity

Naphthalimide-Containing BP100 Leads to Higher Model Membranes Interactions and Antimicrobial Activity

In a large variety of organisms, antimicrobial peptides (AMPs) are primary defenses against pathogens. BP100 (KKLFKKILKYL-NH<sub>2</sub>), a short, synthetic, cationic AMP, is active against bacteria and displays low toxicity towards eukaryotic cells. BP100 acquires a α-helical conformat...

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Bibliographic Details
Main Authors: Gustavo Penteado Battesini Carretero, Greice Kelle Viegas Saraiva, Magali Aparecida Rodrigues, Sumika Kiyota, Marcelo Porto Bemquerer, Hernan Chaimovich, Iolanda Midea Cuccovia
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Biomolecules
Subjects:
antimicrobial peptide
BP100
model membranes
spectroscopy
calorimetry
biological activity
Online Access:https://www.mdpi.com/2218-273X/11/4/542

Internet

https://www.mdpi.com/2218-273X/11/4/542

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