d-serine availability modulates prefrontal cortex inhibitory interneuron development and circuit maturation

d-serine availability modulates prefrontal cortex inhibitory interneuron development and circuit maturation

Abstract The proper development and function of telencephalic GABAergic interneurons is critical for maintaining the excitation and inhibition (E/I) balance in cortical circuits. Glutamate contributes to cortical interneuron (CIN) development via N-methyl-d-aspartate receptors (NMDARs). NMDAR activa...

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Main Authors: Oluwarotimi O. Folorunso, Stephanie E. Brown, Jugajyoti Baruah, Theresa L. Harvey, Shekib A. Jami, Inna Radzishevsky, Herman Wolosker, James M. McNally, John A. Gray, Anju Vasudevan, Darrick T. Balu
Format: Article
Language:English
Published: Nature Portfolio 2023-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-35615-5

Internet

https://doi.org/10.1038/s41598-023-35615-5

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