Utilizing immunogenomic approaches to prioritize targetable neoantigens for personalized cancer immunotherapy

Utilizing immunogenomic approaches to prioritize targetable neoantigens for personalized cancer immunotherapy

Advancements in sequencing technologies and bioinformatics algorithms have expanded our ability to identify tumor-specific somatic mutation-derived antigens (neoantigens). While recent studies have shown neoantigens to be compelling targets for cancer immunotherapy due to their foreign nature and hi...

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Bibliographic Details
Main Authors: Ravi K. Shah, Erin Cygan, Tanya Kozlik, Alfredo Colina, Anthony E. Zamora
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-12-01
Series:Frontiers in Immunology
Subjects:
cancer immunotherapy
immunogenomics
neoantigens
genomics-based approaches
single-cell technologies
immunogenic neoepitopes
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1301100/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1301100/full

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