Low avidity circulating SARS-CoV-2 reactive CD8+ T cells with proinflammatory TEMRA phenotype are associated with post-acute sequelae of COVID-19

Low avidity circulating SARS-CoV-2 reactive CD8+ T cells with proinflammatory TEMRA phenotype are associated with post-acute sequelae of COVID-19

The role of adaptive SARS-CoV-2 specific immunity in post-acute sequelae of COVID-19 (PASC) is not well explored, although a growing population of convalescent COVID-19 patients with manifestation of PASC is observed. We analyzed the SARS-CoV-2-specific immune response, via pseudovirus neutralizing...

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Bibliographic Details
Main Authors: Krystallenia Paniskaki, Margarethe J. Konik, Moritz Anft, Harald Heidecke, Toni L. Meister, Stephanie Pfaender, Adalbert Krawczyk, Markus Zettler, Jasmin Jäger, Anja Gaeckler, Sebastian Dolff, Timm H. Westhoff, Hana Rohn, Ulrik Stervbo, Carmen Scheibenbogen, Oliver Witzke, Nina Babel
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Microbiology
Subjects:
post-acute sequelae of COVID-19
PASC
long COVID
T cells
BMI
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2023.1196721/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2023.1196721/full

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