Monosodium iodoacetate-induced subchondral bone microstructure and inflammatory changes in an animal model of osteoarthritis

The monosodium iodoacetate (MIA)-induced osteoarthritis (OA) may lead to cartilage degeneration and histopathological lesions. However, the correlation between inflammatory reaction and subchondral bone remodeling in a rodent osteoarthritic model is ambiguous. In this study, intra-articular injectio...

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Bibliographic Details
Main Authors: Bao Zheming, Chen Mengli, Li Chen, Shan Qing, Wang Yichen, Yang Wenshan
Format: Article
Language:English
Published: De Gruyter 2022-07-01
Series:Open Life Sciences
Subjects:
Online Access:https://doi.org/10.1515/biol-2022-0079