Propofol protects against high glucose-mediated endothelial injury via inhibition of COX2 and iNOS expressions

Propofol protects against high glucose-mediated endothelial injury via inhibition of COX2 and iNOS expressions

Perioperative hyperglycemia is a common metabolic disorder in the clinic. Hyperglycemia, via upregulation of E74-like ETS transcription factor 3 (ELF3), induces cyclooxygenase 2 (COX2) and inducible nitric oxide synthase (iNOS) expressions, thus leading to endothelial apoptosis and vascular endothel...

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Bibliographic Details
Main Authors: Shao Jiayun, Ding Juan, Lu Lihong, Hou Wenting, Wang Fei, Sun Zhirong, Jiang Hui, Zhao Yanjun
Format: Article
Language:English
Published: China Science Publishing & Media Ltd. 2022-03-01
Series:Acta Biochimica et Biophysica Sinica
Subjects:
propofol
high glucose
COX2
iNOS
SP1
Online Access:https://www.sciengine.com/doi/10.3724/abbs.2022020

Internet

https://www.sciengine.com/doi/10.3724/abbs.2022020

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