Propofol protects against high glucose-mediated endothelial injury via inhibition of COX2 and iNOS expressions

Propofol protects against high glucose-mediated endothelial injury via inhibition of COX2 and iNOS expressions

Perioperative hyperglycemia is a common metabolic disorder in the clinic. Hyperglycemia, via upregulation of E74-like ETS transcription factor 3 (ELF3), induces cyclooxygenase 2 (COX2) and inducible nitric oxide synthase (iNOS) expressions, thus leading to endothelial apoptosis and vascular endothel...

ver descrição completa

Detalhes bibliográficos
Main Authors:	Shao Jiayun, Ding Juan, Lu Lihong, Hou Wenting, Wang Fei, Sun Zhirong, Jiang Hui, Zhao Yanjun
Formato:	Artigo
Idioma:	English
Publicado em:	China Science Publishing & Media Ltd. 2022-03-01
Colecção:	Acta Biochimica et Biophysica Sinica
Assuntos:	propofol high glucose COX2 iNOS SP1
Acesso em linha:	https://www.sciengine.com/doi/10.3724/abbs.2022020

Registos relacionados

iNOS is associated with tumorigenicity as an independent prognosticator in human intrahepatic cholangiocarcinoma
Por: Liu S, et al.
Publicado em: (2019-08-01)

Cuantificación de células endoteliales que expresan VEGF, iNOS y eNOS en el endometrio ovino a los 20, 28 y 35 días de la gestación Quantification of endothelial cells expressing VEGF, iNOS and eNOS in the ovine endometrium at 20, 28 and 35 days of gestation
Por: Piedad C Rivas, et al.
Publicado em: (2007-09-01)

Maprotiline inhibits COX2 and iNOS gene expression in lipopolysaccharide-stimulated U937 macrophages and carrageenan-induced paw edema in rats
Por: Laleh Rafiee, et al.
Publicado em: (2019-04-01)

Upregulation of iNOS and phosphorylated eNOS in the implantation‐induced blastocysts of mice
Por: Misato Seki, et al.
Publicado em: (2023-01-01)

iNOS polymorphism modulates iNOS/NO expression via impaired antioxidant and ROS content in P. vivax and P. falciparum infection
Por: Amod Kumar, et al.
Publicado em: (2018-05-01)

Supplementation of syringic acid-rich Phrynium pubinerve leaves imparts protection against allergic inflammatory responses by downregulating iNOS, COX-2, and NF-κB expressions
Por: Md Arman Islam, et al.
Publicado em: (2023-02-01)

iNOS Induces Vascular Endothelial Cell Migration and Apoptosis Via Autophagy in Ischemia/Reperfusion Injury
Por: Tiebing Zhu, et al.
Publicado em: (2016-04-01)

iNOS expressing macrophages co-localize with nitrotyrosine staining after myocardial infarction in humans
Por: Verena Wilmes, et al.
Publicado em: (2023-03-01)

Inhibition of LPS-Induced Oxidative Damages and Potential Anti-Inflammatory Effects of <i>Phyllanthus emblica</i> Extract via Down-Regulating NF-κB, COX-2, and iNOS in RAW 264.7 Cells
Por: Hui Min-David Wang, et al.
Publicado em: (2019-08-01)

Targeting iNOS to increase efficacy of immunotherapies
Por: Suhendan Ekmekcioglu, et al.
Publicado em: (2017-05-01)

Neuroimmunomodulation in Chronic Wound Healing after Treatment with Photodynamic Therapy: The Role of iNOs
Por: Lorenzo Notari, et al.
Publicado em: (2023-03-01)

Role of iNOS and eNOS expression in a group of Egyptian diabetic and nondiabetic nephropathy patients
Por: Mayssa I. Aly, et al.
Publicado em: (2013-01-01)

The Effects of Bee Venom on PLA2, COX-2, iNOS, AA and PG in RAW 264.7 Cells
Por: Hyun-Chul Jo, et al.
Publicado em: (2002-12-01)

Therapeutic effects of iNOS inhibition against vitiligo in an animal model
Por: Hamid Mansourpour, et al.
Publicado em: (2019-08-01)

Myosin V and iNOS expression is enhanced in J774 murine macrophages treated with IFN-gamma
Por: D.S. Reis, et al.
Publicado em: (2001-02-01)

Pharmacological or genetic inhibition of iNOS prevents cachexia‐mediated muscle wasting and its associated metabolism defects
Por: Jason Sadek, et al.
Publicado em: (2021-06-01)

iNOS Deletion in Alveolar Epithelium Cannot Reverse the Elastase-Induced Emphysema in Mice
Por: Marija Gredic, et al.
Publicado em: (2022-12-01)

Obesity, inflammation, and exercise training: relative contribution of iNOS and eNOS in the modulation of vascular function in the mouse aorta
Por: Josiane Fernandes da Silva, et al.
Publicado em: (2016-09-01)

Integrative Bioinformatics Analysis of iNOS/NOS2 in gastric and colorectal cancer
Por: Lu Mingbei, et al.
Publicado em: (2020-12-01)

Effects of Contamination Detergent (Las) On The Expression Of iNOS In Kidney Common Carp (Cyprinus carpio L.)
Por: Ruku R. Borut
Publicado em: (2014-01-01)

Quercetin modulates iNOS, eNOS and NOSTRIN expressions and attenuates oxidative stress in warm hepatic ischemia-reperfusion injury in rats
Por: Mohamed Abd-Elbaset, et al.
Publicado em: (2015-09-01)

Aging alters the production of iNOS, arginase and cytokines in murine macrophages
Por: C.A. Cecílio, et al.
Publicado em: (2011-07-01)

Human umbilical cord expresses several vasoactive peptides involved in the local regulation of vascular tone: protein and gene expression of Orphanin, Oxytocin, ANP, eNOS and iNOS
Por: Aldo Gerbino, et al.
Publicado em: (2011-07-01)

Effect of aminoguanidine and albendazole on inducible nitric oxide synthase (iNOS) activity in <i>T. spiralis</i>-infected mice muscles
Por: Iwona Mozer-Lisewska, et al.
Publicado em: (2011-08-01)

iNOS contributes to heart failure with preserved ejection fraction through mitochondrial dysfunction and Akt S-nitrosylation
Por: Yongzheng Guo, et al.
Publicado em: (2023-01-01)

Replication of Salmonella enterica serovar Typhimurium in RAW264.7 Phagocytes Correlates With Hypoxia and Lack of iNOS Expression
Por: Marie Wrande, et al.
Publicado em: (2020-11-01)

Paneth cell-derived iNOS is required to maintain homeostasis in the intestinal stem cell niche
Por: Lingxiao Huang, et al.
Publicado em: (2023-11-01)

The Breast Cancer Protooncogenes HER2, BRCA1 and BRCA2 and Their Regulation by the iNOS/NOS2 Axis
Por: Katie Lin, et al.
Publicado em: (2022-06-01)

Dengue induces iNOS expression and nitric oxide synthesis in platelets through IL-1R
Por: Mariana Brandi Mendonça Pinheiro, et al.
Publicado em: (2022-12-01)

Lavandula viridis L´Hér. Essential Oil Inhibits the Inflammatory Response in Macrophages Through Blockade of NF-KB Signaling Cascade
Por: Monica Zuzarte, et al.
Publicado em: (2022-01-01)

Fragilides K and L, New Briaranes from the Gorgonian Coral Junceella fragilis
Por: Li-Guo Zheng, et al.
Publicado em: (2018-06-01)

Turmeric Extract (<i>Curcuma longa</i>) Mediates Anti-Oxidative Effects by Reduction of Nitric Oxide, iNOS Protein-, and mRNA-Synthesis in BV2 Microglial Cells
Por: Jana Streyczek, et al.
Publicado em: (2022-01-01)

Vitexin alleviates breast tumor in mice via skewing TAMs toward an iNOS+ profile orchestrating effective CD8+ T cell activation
Por: Yonger Chen, et al.
Publicado em: (2022-08-01)

Effects of Mongolian Warm Acupuncture on iNOS/NO and Inflammatory Cytokines in the Hippocampus of Chronic Fatigue Rats
Por: Ling Shui, et al.
Publicado em: (2020-01-01)

iNOS is not responsible for RyR1 S-nitrosylation in mdx mice with truncated dystrophin
Por: Ken’ichiro Nogami, et al.
Publicado em: (2020-07-01)

Mild Hyperthermia Accelerates Bone Repair by Dynamically Regulating iNOS/Arg1 Balance in the Early Stage
Por: Jinhui Zhao, et al.
Publicado em: (2025-02-01)

Macrophage Reprogramming and Cancer Therapeutics: Role of iNOS-Derived NO
Por: Khosrow Kashfi, et al.
Publicado em: (2021-11-01)

Reduced Retinal Degeneration in an Oxidative Stress Organ Culture Model through an iNOS-Inhibitor
Por: Ana M. Mueller-Buehl, et al.
Publicado em: (2021-04-01)

Cell Origin and iNOS Function Are Critical to Macrophage Activation Following Acute Lung Injury
Por: Thea N. Golden, et al.
Publicado em: (2022-01-01)

Monitoring the immune response of macrophages in tuberculous granuloma through the expression of CD68, iNOS and HLA-DR in naturally infected beef cattle
Por: Mohamed G. Hamed, et al.
Publicado em: (2023-10-01)