The rs78378222 prevalence and the copy loss of the protective allele A in the tumor tissue of diffuse large B-cell lymphoma

Background Rare single nucleotide polymorphisms (SNPs) are likely to be a crucial genetic factor for human diseases, including cancer. rs78378222 is rare SNP in 3′-untranslated region (UTR) of TP53 gene leading to disturbance of 3′-end mRNA processing. The frequency of rs78378222 varies in several s...

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Bibliographic Details
Main Authors: Elena N. Voropaeva, Yuriy L. Orlov, Tatiana I. Pospelova, Anna A. Gurageva, Mikhail I. Voevoda, Vladimir N. Maksimov, Olga B. Seregina, Maria I. Churkina
Format: Article
Language:English
Published: PeerJ Inc. 2020-11-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/10335.pdf