Investigation of monoclonal antibody CSX-1004 for fentanyl overdose

Abstract The opioid crisis in the United States is primarily driven by the highly potent synthetic opioid fentanyl leading to >70,000 overdose deaths annually; thus, new therapies for fentanyl overdose are urgently needed. Here, we present the first clinic-ready, fully human monoclonal antibody C...

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Bibliographic Details
Main Authors: Paul T. Bremer, Emily L. Burke, Andrew C. Barrett, Rajeev I. Desai
Format: Article
Language:English
Published: Nature Portfolio 2023-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-43126-0