HLA-associated immune pressure on Gag protein in CRF01_AE-infected individuals and its association with plasma viral load.

BACKGROUND: The human leukocyte antigen (HLA)-restricted cytotoxic T-lymphocyte (CTL) immune response is one of the major factors determining the genetic diversity of human immunodeficiency virus (HIV). There are few population-based analyses of the amino acid variations associated with the host HLA...

Full description

Bibliographic Details
Main Authors: Goragoch Gesprasert, Nuanjun Wichukchinda, Masahiko Mori, Teiichiro Shiino, Wattana Auwanit, Busarawan Sriwanthana, Panita Pathipvanich, Pathom Sawanpanyalert, Toshiyuki Miura, Prasert Auewarakul, Arunee Thitithanyanont, Koya Ariyoshi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2887364?pdf=render