Metabolic engineering of Streptomyces to enhance the synthesis of valuable natural products
The mycelial bacterium Streptomyces is a workhorse for producing natural products, serving as a key source of drugs and other valuable chemicals. However, its complicated life cycle, silent biosynthetic gene clusters (BGCs), and poorly characterized metabolic mechanisms limit efficient production of...
Main Authors: | , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2022-06-01
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Series: | Engineering Microbiology |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2667370322000133 |