Treg engage lymphotoxin beta receptor for afferent lymphatic transendothelial migration

Lymphotoxin regulates lymphoid organ architecture and adhesion molecules involved in lymphocyte trafficking. Here the authors show that lymphotoxin produced by regulatory T cells promotes their migration to the draining lymph nodes by engaging its cognate receptor on lymphatic endothelial cells.

Xehetasun bibliografikoak
Egile Nagusiak: C. Colin Brinkman, Daiki Iwami, Molly K. Hritzo, Yanbao Xiong, Sarwat Ahmad, Thomas Simon, Keli L. Hippen, Bruce R. Blazar, Jonathan S. Bromberg
Formatua: Artikulua
Hizkuntza:English
Argitaratua: Nature Portfolio 2016-06-01
Saila:Nature Communications
Sarrera elektronikoa:https://doi.org/10.1038/ncomms12021