The conserved RNA helicase YTHDC2 regulates the transition from proliferation to differentiation in the germline

The switch from mitosis to meiosis is the key event marking onset of differentiation in the germline stem cell lineage. In Drosophila, the translational repressor Bgcn is required for spermatogonia to stop mitosis and transition to meiotic prophase and the spermatocyte state. Here we show that the m...

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Bibliographic Details
Main Authors: Alexis S Bailey, Pedro J Batista, Rebecca S Gold, Y Grace Chen, Dirk G de Rooij, Howard Y Chang, Margaret T Fuller
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2017-10-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/26116