Pirfenidone regulates antioxidant response via NRF2 in an experimental model of hepatocellular carcinoma
Introduction and Objectives: 1) Determinate if pirfenidone (PFD) modifies oxidative stress markers. 2) Evaluate PFD effects on transcription factor Nrf2 signaling pathway. Materials and methods: Eighteen Fischer-344 rats divided into three groups were used: 1) untreated (NT), 2) carcinogenic damage...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2022-12-01
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| Series: | Annals of Hepatology |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1665268122001983 |