MAGI2-AS3 restrains proliferation, glycolysis, and triggers apoptosis in acute lymphoblastic leukemia via regulating miR-452-5p/FOXN3 pathway

Objective(s): MAGI2-AS3 is a cancer suppressor gene of multiple malignancies. Acute lymphoblastic leukemia (ALL) is an important type of leukemia that especially occurs in children. Our work evaluated the modulation of MAGI2-AS3 in ALL.Materials and Methods: qPCR and Western blotting were adopted fo...

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Bibliographic Details
Main Authors: Xiao-Guang Chen, Bing-Hua Dou, Jin-Dou An, Song Feng, Na Liu, Guang-Yao Sheng
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2022-01-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
Online Access:https://ijbms.mums.ac.ir/article_19301_2880897d75bd5e6d764067c82942d63b.pdf