Therapeutic Effects of Treatment with Anti-TLR2 and Anti-TLR4 Monoclonal Antibodies in Polymicrobial Sepsis.

Toll-like receptors (TLRs) play an important role in the recognition of microbial products and in host defense against infection. However, the massive release of inflammatory mediators into the bloodstream following TLR activation following sepsis is thought to contribute to disease pathogenesis.Her...

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Библиографические подробности
Главные авторы: Cristiano Xavier Lima, Danielle Gloria Souza, Flavio Almeida Amaral, Caio Tavares Fagundes, Irla Paula Stopa Rodrigues, Jose Carlos Alves-Filho, Marie Kosco-Vilbois, Walter Ferlin, Limin Shang, Greg Elson, Mauro Martins Teixeira
Формат: Статья
Язык:English
Опубликовано: Public Library of Science (PLoS) 2015-01-01
Серии:PLoS ONE
Online-ссылка:http://europepmc.org/articles/PMC4492955?pdf=render