Therapeutic Effects of Treatment with Anti-TLR2 and Anti-TLR4 Monoclonal Antibodies in Polymicrobial Sepsis.
Toll-like receptors (TLRs) play an important role in the recognition of microbial products and in host defense against infection. However, the massive release of inflammatory mediators into the bloodstream following TLR activation following sepsis is thought to contribute to disease pathogenesis.Her...
Главные авторы: | , , , , , , , , , , |
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Формат: | Статья |
Язык: | English |
Опубликовано: |
Public Library of Science (PLoS)
2015-01-01
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Серии: | PLoS ONE |
Online-ссылка: | http://europepmc.org/articles/PMC4492955?pdf=render |