<i>BACH1</i> Expression Is Promoted by Tank Binding Kinase 1 (<i>TBK1</i>) in Pancreatic Cancer Cells to Increase Iron and Reduce the Expression of E-Cadherin

<i>BACH1</i> Expression Is Promoted by Tank Binding Kinase 1 (<i>TBK1</i>) in Pancreatic Cancer Cells to Increase Iron and Reduce the Expression of E-Cadherin

BTB and CNC homology 1 (<i>BACH1</i>) represses the expression of genes involved in the metabolism of iron, heme and reactive oxygen species and promotes metastasis of various cancers including pancreatic ductal adenocarcinoma (PDAC). However, it is not clear how <i>BACH1</i>...

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Bibliographic Details
Main Authors: Liang Liu, Mitsuyo Matsumoto, Miki Matsui-Watanabe, Kyoko Ochiai, Bert K. K. Callens, Long Chi Nguyen, Yushi Kozuki, Miho Tanaka, Hironari Nishizawa, Kazuhiko Igarashi
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Antioxidants
Subjects:
<i>BACH1</i>
<i>TBK1</i>
iron
ferritin
pancreatic cancer
Online Access:https://www.mdpi.com/2076-3921/11/8/1460

Internet

https://www.mdpi.com/2076-3921/11/8/1460

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