Estradiol matrix patches for pubertal induction: stability of cut pieces at different temperatures

Objective: Transdermal estradiol patches are primarily designed for adult women. No low-dose patches are licensed for pubertal induction in hypogonadal girls. Low doses can be achieved by cutting a matrix patch into smaller pieces. However, the manufacturers do not guarantee stability or utility of...

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Bibliographic Details
Main Authors: Carina Ankarberg-Lindgren, Aneta Gawlik, Berit Kriström, Laura Mazzanti, Elisabeth J Ruijgrok, Theo C J Sas
Format: Article
Language:English
Published: Bioscientifica 2019-03-01
Series:Endocrine Connections
Subjects:
Online Access:https://ec.bioscientifica.com/view/journals/ec/8/4/EC-19-0025.xml