Complement Is Activated During Normothermic Machine Perfusion of Porcine and Human Discarded Kidneys

Complement Is Activated During Normothermic Machine Perfusion of Porcine and Human Discarded Kidneys

BackgroundThe gap between demand and supply of kidneys for transplantation necessitates the use of kidneys from extended criteria donors. Transplantation of these donor kidneys is associated with inferior results, reflected by an increased risk of delayed graft function. Inferior results might be ex...

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Bibliographic Details
Main Authors: Neeltina M. Jager, Leonie H. Venema, Asel S. Arykbaeva, Anita H. Meter-Arkema, Petra J. Ottens, Cees van Kooten, Tom E. Mollnes, Ian P. J. Alwayn, Henri G. D. Leuvenink, Soeren E. Pischke, PROPER study consortium
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Immunology
Subjects:
kidney transplantation
normothermic machine perfusion
complement system
ischemia-reperfusion injury
immunology
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.831371/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2022.831371/full

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