Hepatoprotective Activity of Lignin-Derived Polyphenols Dereplicated Using High-Resolution Mass Spectrometry, In Vivo Experiments, and Deep Learning

Hepatoprotective Activity of Lignin-Derived Polyphenols Dereplicated Using High-Resolution Mass Spectrometry, In Vivo Experiments, and Deep Learning

Chronic liver diseases affect more than 1 billion people worldwide and represent one of the main public health issues. Nonalcoholic fatty liver disease (NAFLD) accounts for the majority of mortal cases, while there is no currently approved therapeutics for its treatment. One of the prospective appro...

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Bibliographic Details
Main Authors: Alexey Orlov, Savva Semenov, Gleb Rukhovich, Anastasia Sarycheva, Oxana Kovaleva, Alexander Semenov, Elena Ermakova, Ekaterina Gubareva, Anna E. Bugrova, Alexey Kononikhin, Elena I. Fedoros, Evgeny Nikolaev, Alexander Zherebker
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:International Journal of Molecular Sciences
Subjects:
NAFLD
hepatoprotective activity
complex mixtures
polyphenolic composition
dereplication
labeling
Online Access:https://www.mdpi.com/1422-0067/23/24/16025

Internet

https://www.mdpi.com/1422-0067/23/24/16025

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