Virtual screening of novel pyridine derivatives as effective inhibitors of DNA gyrase (GyrA) of salmonella typhi

In a bid to discovering novel antibiotics to combat growing trend of multi-drug resistance strains of Salmonella typhi, 48 new pyridine derivatives with significant inhibitory activities against the aforementioned bacterium were subjected to molecular docking against DNA gyrase protease of...

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Bibliographic Details
Main Authors: John Ameji Philip, Adamu Uzairu, Gideon Adamu Shallangwa, Sani Uba
Format: Article
Language:English
Published: Growing Science 2023-01-01
Series:Current Chemistry Letters
Online Access:http://www.growingscience.com/ccl/Vol12/ccl_2022_46.pdf