Therapeutic effects of shaogan fuzi decoction in rheumatoid arthritis: Network pharmacology and experimental validation

Therapeutic effects of shaogan fuzi decoction in rheumatoid arthritis: Network pharmacology and experimental validation

Shaogan Fuzi Decoction (SGFD), one of the classical prescriptions of Chinese Medicine, has a long history in the treatment of rheumatoid arthritis (RA), but definitive studies on its efficacy and mechanism of action are lacking. This study aims to elucidate the pharmacodynamic role of SGFD against R...

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Bibliographic Details
Main Authors: Lu Shi, Yiying Zhao, Chenran Feng, Feng Miao, Linlin Dong, Tianquan Wang, Antony Stalin, Jingyuan Zhang, Jingru Tu, Kexin Liu, Wenyan Sun, Jiarui Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Pharmacology
Subjects:
shaogan fuzi Decoction
rheumatoid arthritis
network pharmacology
TLR4/MAPKs/NF-κB signaling pathway
inflammatory
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.967164/full

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https://www.frontiersin.org/articles/10.3389/fphar.2022.967164/full

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