Peripheral nerve repair is associated with augmented cross-tissue inflammation following vascularized composite allotransplantation

Peripheral nerve repair is associated with augmented cross-tissue inflammation following vascularized composite allotransplantation

IntroductionVascularized composite allotransplantation (VCA), with nerve repair/coaptation (NR) and tacrolimus (TAC) immunosuppressive therapy, is used to repair devastating traumatic injuries but is often complicated by inflammation spanning multiple tissues. We identified the parallel upregulation...

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Bibliographic Details
Main Authors: Ashti M. Shah, Ali Mubin Aral, Ruben Zamora, Nitin Gharpure, Fayten El-Dehaibi, Fatih Zor, Yalcin Kulahci, Huseyin Karagoz, Derek A. Barclay, Jinling Yin, Warren Breidenbach, Dmitry Tuder, Vijay S. Gorantla, Yoram Vodovotz
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Immunology
Subjects:
transplantation
nerve-repair
inflammation
cross-tissue
systems biology
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1151824/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1151824/full

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