Paeoniflorin Protects against Acetaminophen-Induced Liver Injury in Mice via JNK Signaling Pathway

Paeoniflorin Protects against Acetaminophen-Induced Liver Injury in Mice via JNK Signaling Pathway

Background: Drug-induced liver injury (DILI), represented by acetaminophen (APAP), is a common cause of acute liver failure in clinics. Paeoniflorin (PF) has been proven to demonstrate a significant hepatoprotective effect. However, it is still unclear whether it can be a potential agent against hep...

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Bibliographic Details
Main Authors: Xinyu Deng, Yubing Li, Xing Li, Zhenpeng Zhang, Shu Dai, Hefei Wu, Fangling Zhang, Qichao Hu, Yuan Chen, Jinhao Zeng, Xiao Ma
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Molecules
Subjects:
paeoniflorin
acetaminophen
drug-induced liver injury
JNK signal
mitochondrial control of apoptosis
Online Access:https://www.mdpi.com/1420-3049/27/23/8534

Internet

https://www.mdpi.com/1420-3049/27/23/8534

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