Methoxyphenyl Imidazolines as Potential Activators of p53
The use of p53-MDM2/X inhibitors is a prospective strategy in anti-cancer therapy for tumors with wild type p53 protein. In our study, new low-molecular-weight inhibitors of the p53-mdm2 interaction have been proposed. The two-step synthesis of the imidazoline core with subsequent modifications for...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2022-11-01
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Series: | Medical Sciences Forum |
Subjects: | |
Online Access: | https://www.mdpi.com/2673-9992/14/1/100 |