Characterisation of functional deficits induced by AAV overexpression of alpha-synuclein in rats

Characterisation of functional deficits induced by AAV overexpression of alpha-synuclein in rats

Background: In the last decades different preclinical animal models of Parkinson's disease (PD) have been generated, aiming to mimic the progressive neuronal loss of midbrain dopaminergic (DA) cells as well as motor and non-motor impairment. Among all the available models, AAV-based models of h...

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Bibliographic Details
Main Authors: F. Gubinelli, L. Sarauskyte, C. Venuti, I. Kulacz, G. Cazzolla, M. Negrini, D. Anwer, I. Vecchio, F. Jakobs, F.P. Manfredsson, M. Davidsson, A. Heuer
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Current Research in Neurobiology
Subjects:
Parkinson's disease
Choice reaction time
Alpha-synuclein
AAV
Visuo-spatial neglect
Online Access:http://www.sciencedirect.com/science/article/pii/S2665945X22000389

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http://www.sciencedirect.com/science/article/pii/S2665945X22000389

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