Derivation of neural stem cells from human adult peripheral CD34+ cells for an autologous model of neuroinflammation.

Proinflammatory factors from activated T cells inhibit neurogenesis in adult animal brain and cultured human fetal neural stem cells (NSC). However, the role of inhibition of neurogenesis in human neuroinflammatory diseases is still uncertain because of the difficulty in obtaining adult NSC from pat...

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Bibliographic Details
Main Authors: Tongguang Wang, Elliot Choi, Maria Chiara G Monaco, Emilie Campanac, Marie Medynets, Thao Do, Prashant Rao, Kory R Johnson, Abdel G Elkahloun, Gloria Von Geldern, Tory Johnson, Sriram Subramaniam, Dax A Hoffman, Eugene Major, Avindra Nath
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3841177?pdf=render