Prostate cancer small extracellular vesicles participate in androgen-independent transformation of prostate cancer by transferring let-7a-5p

Prostate cancer small extracellular vesicles participate in androgen-independent transformation of prostate cancer by transferring let-7a-5p

Objectives: Androgen deprivation therapy (ADT) is a standard treatment for advanced prostate cancer (PCa). However, after 2–3 years ADT treatment, prostate cancer inevitably transits from androgen-dependent PCa (ADPC) to androgen-independent PCa (AIPC), which has a poor prognosis owing to its unclea...

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Bibliographic Details
Main Authors: Lin Lei, Lijuan Yu, Weixiao Fan, Xiaoke Hao
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Heliyon
Subjects:
Androgen-independent PCa
Androgen-dependent PCa
Castration-resistant PCa
Let-7a-5p
Androgen receptor signaling pathway
PI3K/Akt signaling pathway
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844022034028

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http://www.sciencedirect.com/science/article/pii/S2405844022034028

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