Implications of Pharmacokinetic Potentials of Pioglitazone Enantiomers in Rat Plasma Mediated through Glucose Uptake Assay

Implications of Pharmacokinetic Potentials of Pioglitazone Enantiomers in Rat Plasma Mediated through Glucose Uptake Assay

Pioglitazone, a PPAR-gamma activator used to diagnose hyperglycemia, was studied for its stereoselective deposition and active enantiomers in female albino Wistar rats. In accordance with USFDA recommendations, a bioanalytical technique was employed to assess the segregation of pioglitazone enantiom...

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Bibliographic Details
Main Authors: Tatineni Spandana, Veera Venkata Nishanth Goli, Mohamed Rahamathulla, Sirajunisa Talath, Riyaz Ali M. Osmani, Mohammed Muqtader Ahmed, Syeda Ayesha Farhana, Shalam Mohamed Hussain, Bannimath Gurupadayya
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Molecules
Subjects:
pioglitazone enantiomers
enantiomeric separation
validation
non-radioactive glucose uptake assay
stereoselectivity
pharmacokinetics
Online Access:https://www.mdpi.com/1420-3049/28/13/4911

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https://www.mdpi.com/1420-3049/28/13/4911

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