Combined In Vivo Microdialysis and PET Studies to Validate [<sup>11</sup>C]Yohimbine Binding as a Marker of Noradrenaline Release

Combined In Vivo Microdialysis and PET Studies to Validate [<sup>11</sup>C]Yohimbine Binding as a Marker of Noradrenaline Release

The noradrenaline system attracts attention for its role in mood disorders and neurodegenerative diseases but the lack of well-validated methods impairs our understanding when assessing its function and release in vivo. This study combines simultaneous positron emission tomography (PET) and microdia...

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Bibliographic Details
Main Authors: Anne Marlene Landau, Steen Jakobsen, Majken Borup Thomsen, Aage Kristian Olsen Alstrup, Dariusz Orlowski, Jan Jacobsen, Gregers Wegener, Arne Mørk, Jens Christian Hedemann Sørensen, Doris J. Doudet
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Biomolecules
Subjects:
a2 adrenoceptors
noradrenaline
microdialysis
minipig
positron emission tomography
[<sup>11</sup>C]yohimbine
Online Access:https://www.mdpi.com/2218-273X/13/4/674

Internet

https://www.mdpi.com/2218-273X/13/4/674

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