The extended cleavage specificity of human thrombin.

Thrombin is one of the most extensively studied of all proteases. Its central role in the coagulation cascade as well as several other areas has been thoroughly documented. Despite this, its consensus cleavage site has never been determined in detail. Here we have determined its extended substrate r...

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Bibliographic Details
Main Authors: Maike Gallwitz, Mattias Enoksson, Michael Thorpe, Lars Hellman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3288055?pdf=render