Hypoxia Promotes Mitochondrial Complex I Abundance via HIF-1α in Complex III and Complex IV Deficient Cells

Hypoxia Promotes Mitochondrial Complex I Abundance via HIF-1α in Complex III and Complex IV Deficient Cells

Murine fibroblasts deficient in mitochondria respiratory complexes III (CIII) and IV (CIV) produced by either the ablation of <i>Uqcrfs1</i> (encoding for Rieske iron sulfur protein, RISP) or <i>Cox10</i> (encoding for protoheme IX farnesyltransferase, COX10) genes, respectiv...

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Bibliographic Details
Main Authors: Amy Saldana-Caboverde, Nadee Nissanka, Sofia Garcia, Anne Lombès, Francisca Diaz
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Cells
Subjects:
mitochondrial respiratory supercomplexes
oxidative phosphorylation
hypoxia
complex I
complex III
complex IV
Online Access:https://www.mdpi.com/2073-4409/9/10/2197

Internet

https://www.mdpi.com/2073-4409/9/10/2197

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