Metformin sensitizes hypoxia-induced gefitinib treatment resistance of HNSCC via cell cycle regulation and EMT reversal

Metformin sensitizes hypoxia-induced gefitinib treatment resistance of HNSCC via cell cycle regulation and EMT reversal

Xiteng Yin,1,2,* Zheng Wei,1,2,* Chuanhui Song,1,2 Chuanchao Tang,1,2 Wenguang Xu,1,2 Yufeng Wang,1,2 Junqi Xie,1,2 Zitong Lin,2,3 Wei Han1,2 1Department of Oral and Maxillofacial Surgery, Nanjing Stomatological Hospital, Medical School of Nanjing University, Nanjing, China; 2Central Laboratory of S...

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Bibliographic Details
Main Authors: Yin XT, Wei Z, Song CH, Tang CC, Xu WG, Wang YF, Xie JQ, Lin ZT, Han W
Format: Article
Language:English
Published: Dove Medical Press 2018-11-01
Series:Cancer Management and Research
Subjects:
Tumor hypoxia
Gefitinib-resistance
Metformin
Online Access:https://www.dovepress.com/metformin-sensitizes-hypoxia-induced-gefitinib-treatment-resistance-of-peer-reviewed-article-CMAR

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https://www.dovepress.com/metformin-sensitizes-hypoxia-induced-gefitinib-treatment-resistance-of-peer-reviewed-article-CMAR

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