Synthesis and Antiproliferative Activity of 2,4,6,7-Tetrasubstituted-2<i>H</i>-pyrazolo[4,3-<i>c</i>]pyridines

Synthesis and Antiproliferative Activity of 2,4,6,7-Tetrasubstituted-2<i>H</i>-pyrazolo[4,3-<i>c</i>]pyridines

A library of 2,4,6,7-tetrasubstituted-2<i>H</i>-pyrazolo[4,3-<i>c</i>]pyridines was prepared from easily accessible 1-phenyl-3-(2-phenylethynyl)-1<i>H</i>-pyrazole-4-carbaldehyde via an iodine-mediated electrophilic cyclization of intermediate 4-(azidomethyl)-1-ph...

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Bibliographic Details
Main Authors: Beatričė Razmienė, Eva Řezníčková, Vaida Dambrauskienė, Radek Ostruszka, Martin Kubala, Asta Žukauskaitė, Vladimír Kryštof, Algirdas Šačkus, Eglė Arbačiauskienė
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Molecules
Subjects:
antiproliferation
cell death
cross-coupling
cycloiodination
pyrazole
pyridine
Online Access:https://www.mdpi.com/1420-3049/26/21/6747

Internet

https://www.mdpi.com/1420-3049/26/21/6747

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