Nrf-2-dependent antioxidant and anti-inflammatory effects underlie the protective effect of esculeoside A against retinal damage in streptozotocin-induced diabetic rats

Nrf-2-dependent antioxidant and anti-inflammatory effects underlie the protective effect of esculeoside A against retinal damage in streptozotocin-induced diabetic rats

Esculeoside A (ESA) is a tomato-derived glycoside with antioxidant and anti-inflammatory properties. The protective effect of ESA against diabetic retinopathy is not well-investigated and was the core objective of this study. In addition, we tested if such protection involves the activation of Nrf2...

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Bibliographic Details
Main Authors: Nasser A. Alsabaani, Kawther Amawi, Samy M. Eleawa, Wisam Nabeel Ibrahim, Walid Aldhaban, Ahmad Mohammad Alaraj, Badr Alkhalaf, Waqas Sami, Hisham Alshaikhli, Mahmoud A. Alkhateeb
Format: Article
Language:English
Published: Elsevier 2024-04-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Esculeoside A
Tomato
Diabetes mellitus
Retina
Nrf2
REDD1
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332224003457

Internet

http://www.sciencedirect.com/science/article/pii/S0753332224003457

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