Combined IgE neutralization and Bifidobacterium longum supplementation reduces the allergic response in models of food allergy
IgE is a critical component of the allergic response and therapeutic targeting can alleviate symptomology. Here the authors propose the combined use of Bifidobacterium longum and a FcεRIα extracellular domain linked to a IgD/IgG4 hybrid Fc domain fusion protein called IgETRAP and show reduction of m...
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Bibliographic Details
| Main Authors: |
Seong Beom An,
Bo-Gie Yang,
Gyeonghui Jang,
Do-Yeon Kim,
Jiyoung Kim,
Sung-Man Oh,
Nahyun Oh,
Sanghee Lee,
Ji-Yeong Moon,
Jeong-Ah Kim,
Ji-Hyun Kim,
Yoo-Jeong Song,
Hye-Won Hyun,
Jisoo Kim,
Kyungwha Lee,
Dajeong Lee,
Min-Jung Kwak,
Byung Kwon Kim,
Young-Kyu Park,
Chun-Pyo Hong,
Jung Hwan Kim,
Hye Seong Lim,
Min Sook Ryu,
Hyun-Tak Jin,
Seung-Woo Lee,
Yoon-Seok Chang,
Hae-Sim Park,
Young Chul Sung,
Myoung Ho Jang |
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| Format: | Article
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| Language: | English |
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| Published: |
Nature Portfolio
2022-09-01
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| Series: | Nature Communications
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| Online Access: | https://doi.org/10.1038/s41467-022-33176-1
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