Aberration in myeloid-derived pro-angiogenic cells in type-2 diabetes mellitus; implication for diabetic retinopathy?

Aberration in myeloid-derived pro-angiogenic cells in type-2 diabetes mellitus; implication for diabetic retinopathy?

PurposeDiabetic retinopathy (DR) is a major microvascular complication of type 2 diabetes mellitus (T2DM). Myelomonocytic proangiogenic cells (PAC) have been implicated in DR pathogenesis, but their functional and developmental abnormalities are unclear. In this study we assessed PAC characteristics...

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Bibliographic Details
Main Authors: Mahnaz Shariatzadeh, Trishika R.R. Binda, Conny van Holten-Neelen, Josianne C. ten Berge, Jose P. Martinez Ciriano, King T. Wong, Willem A. Dik, Pieter J.M. Leenen
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Ophthalmology
Subjects:
diabetic retinopathy
myeloid-derived pro-angiogenic cells
retinal endothelial cells
in vitro angiogenesis
microvascular dysfunction
Online Access:https://www.frontiersin.org/articles/10.3389/fopht.2023.1119050/full

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https://www.frontiersin.org/articles/10.3389/fopht.2023.1119050/full

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